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Caspase 3 Antikörper (active, Cleavage Site, N-Term)

Name: Caspase 3 Antikörper (active, Cleavage Site, N-Term)
SKU: ABIN126957
Price: 706.25 EUR
Availability: InStock

CASP3 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Image no. 1 for anti-Caspase 3 (CASP3) (active), (Cleavage Site), (N-Term) antibody (ABIN126957) (Caspase 3 Antikörper (active, Cleavage Site, N-Term))

1 image

Produktnummer ABIN126957

Datenblatt (PDF)

Target Alle Caspase 3 (CASP3) Antikörper anzeigen

Caspase 3 (CASP3)
Bindungsspezifität
19

16

16

14

13

12

12

10

9

8

8

8

7

6

6

6

5

5

4

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
active, Cleavage Site, N-Term
Reaktivität
215

120

74

17

11

10

9

8

7

5

5

4

3

3

2

2

1

1
Human, Maus, Ratte
Wirt
227

21

4

2

2
Kaninchen
Passende Sekundärantikörper
Klonalität
215

40
Polyklonal
Konjugat
155

20

17

9

8

6

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1
Dieser Caspase 3 Antikörper ist unkonjugiert
Applikation
187

107

102

57

42

35

31

29

28

28

26

11

10

6

3

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität

The antibody preferentially recognizes the p17 fragment of the active caspase-3.

Aufreinigung

Affinity chromatography

Immunogen

Synthetic peptide mapping to the N-terminus adjacent to the cleavage site of human caspase-3

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anti-Caspase 3 (CASP3) (pSer150) antibody
CASP3 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Caspase 3 (CASP3) (Internal Region) antibody
CASP3 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 100-200) antibody
CASP3 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Caspase 3 (CASP3) (cleaved) antibody
CASP3 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 29-175) antibody
CASP3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Caspase 3 (CASP3) (AA 29-175) antibody
CASP3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C3 unconjugated

Applikationshinweise

Western Blot: 0.5-4 μg/mL. Immunohistochemistry on paraffin sections: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.2 mg/mL

Buffer

PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal

Konservierungsmittel

Thimerosal (Merthiolate)

Vorsichtsmaßnahmen

This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

-20 °C/-80 °C

Informationen zur Lagerung

Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C to -70 °C.
Target

Caspase 3 (CASP3)

Andere Bezeichnung

Caspase-3 (CASP3 Produkte)

Hintergrund

Caspase-3 has been extensively studied and implicated to play an important role in apoptosis. Active caspase-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP). The affinity purified antibody recognizing the active forms of caspase-3 provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells.Synonyms: Apopain, CASP-3, CASP3, CPP-32, CPP32, Cysteine protease CPP32, SCA-1, SCA1, SREBP cleavage activity 1, Yama protein

Gen-ID

836

NCBI Accession

NP_004337

UniProt

P42574

Pathways

Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation