Caspase 7 Antikörper (Cleavage Site)
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- Target Alle Caspase 7 (CASP7) Antikörper anzeigen
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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Bindungsspezifität
- Cleavage Site
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Caspase 7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- The antibody detects the full length (35-37 kDa) and the large fragment (20 kDa) of processed caspase-7 by Western blotting.
- Aufreinigung
- Immunoaffinity purified
- Immunogen
- Synthetic peptide corresponding to residues surrounding the cleavage site of human caspase-7 large fragment
- Top Product
- Discover our top product CASP7 Primärantikörper
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- Applikationshinweise
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Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.2 mg/mL
- Buffer
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C/-80 °C
- Informationen zur Lagerung
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- Target
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
- Andere Bezeichnung
- Caspase-7 (CASP7 Produkte)
- Hintergrund
- Caspase-7 is a 34 kDa protein consisting of two subunits and a short prodomain. The procaspase-7 can be activated by cleavage by upstream caspases to form active caspase-7 in apoptosis. Once activated, caspase-7 cleaves many of the same substrates as caspase-3, including poly (ADP-ribose) polymerase (PARP) and sterol regulatory element binding proteins (SREBPs).Synonyms: Apoptotic protease Mch-3, CASP-7, CASP7, CMH-1, ICE-like apoptotic protease 3, MCH3
- Gen-ID
- 840
- NCBI Accession
- NP_001218
- UniProt
- P55210
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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