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Caspase 7 Antikörper (Cleavage Site)

CASP7 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN127023
  • Target Alle Caspase 7 (CASP7) Antikörper anzeigen
    Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
    Bindungsspezifität
    • 15
    • 12
    • 10
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cleavage Site
    Reaktivität
    • 85
    • 56
    • 26
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 81
    • 12
    • 1
    Kaninchen
    Klonalität
    • 81
    • 13
    Polyklonal
    Konjugat
    • 60
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Caspase 7 Antikörper ist unkonjugiert
    Applikation
    • 84
    • 33
    • 26
    • 18
    • 14
    • 13
    • 13
    • 13
    • 9
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Spezifität
    The antibody detects the full length (35-37 kDa) and the large fragment (20 kDa) of processed caspase-7 by Western blotting.
    Aufreinigung
    Immunoaffinity purified
    Immunogen
    Synthetic peptide corresponding to residues surrounding the cleavage site of human caspase-7 large fragment
    Top Product
    Discover our top product CASP7 Primärantikörper
  • Applikationshinweise
    Western Blot: 0.5-4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.2 mg/mL
    Buffer
    PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • Target
    Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
    Andere Bezeichnung
    Caspase-7 (CASP7 Produkte)
    Hintergrund
    Caspase-7 is a 34 kDa protein consisting of two subunits and a short prodomain. The procaspase-7 can be activated by cleavage by upstream caspases to form active caspase-7 in apoptosis. Once activated, caspase-7 cleaves many of the same substrates as caspase-3, including poly (ADP-ribose) polymerase (PARP) and sterol regulatory element binding proteins (SREBPs).Synonyms: Apoptotic protease Mch-3, CASP-7, CASP7, CMH-1, ICE-like apoptotic protease 3, MCH3
    Gen-ID
    840
    NCBI Accession
    NP_001218
    UniProt
    P55210
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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