ING3 Antikörper (AA 285-310)
-
- Target Alle ING3 Antikörper anzeigen
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
-
Bindungsspezifität
- AA 285-310
-
Reaktivität
- Human
-
Wirt
- Ziege
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ING3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Hersteller Produkt- Nr.
- 600-101-283
- Hersteller
- Rockland
- Verwendungszweck
- p47ING3 Antibody
- Kreuzreaktivität (Details)
- Reactivity occurs against human p47 ING3 protein.
- Produktmerkmale
- Synonyms: goat anti-p47 ING3 antibody, p47ING3, ING-3, ING 3, Inhibitor of growth family member 3 antibody, Inhibitor of growth protein 3 antibody
- Aufreinigung
- This is an affinity-purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.
- Sterilität
- Sterile filtered
- Immunogen
-
Immunogen: This affinity purified antibody was prepared from whole Goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 285-310 of Human ING3 protein (Inhibitor of growth family, member 3).
Immunogen Type: Conjugated Peptide
- Isotyp
- IgG
- Top Product
- Discover our top product ING3 Primärantikörper
-
-
- Applikationshinweise
-
Application Note: This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Specific conditions for western blotting reactivity should be optimized by the end user. Expect a band at approximately 47 kDa in size corresponding to ING3 isoform 1 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:200 - 1:2,000
ELISA Dilution: 1:10,000 - 1:40,000
Other: User Optimized
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1.10 mg/mL
- Buffer
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Haltbarkeit
- 12 months
-
- Target
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
- Andere Bezeichnung
- ING3 (ING3 Produkte)
- Hintergrund
- Background: p47 ING3 is a tumor suppressor protein similar to ING1 that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Over-expression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Multiple alternatively spliced transcript variants have been observed. The accession number listed below is for variant (1) that encodes the longest isoform.
- Gen-ID
- 54556, 38201655
- UniProt
- Q9NXR8
-