RAD23A Antikörper (AA 122-135)

Produktnummer ABIN129556

Produktdetails anti-RAD23A Antikörper

Target: RAD23A (RAD23 Homolog A (RAD23A))

Bindungsspezifität: AA 122-135

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser RAD23A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 122-135 of human HR23A protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 60 kDa in size corresponding to HR23A by western blotting in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.2 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-RAD23A Antikörper (ABIN129556)

Zhu, Wani, Arab, El-Mahdy, Ray, Wani: "Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinated H2A at damaged genomic sites." in: DNA repair, Vol. 8, Issue 2, pp. 262-73, (2009) (PubMed).

Details zu RAD23A

Target: RAD23A (RAD23 Homolog A (RAD23A))

Andere Bezeichnung: HR23A (RAD23A Produkte)

Synonyme: rad23a antikoerper, wu:fe11h06 antikoerper, zgc:92001 antikoerper, RAD23A antikoerper, HHR23A antikoerper, HR23A antikoerper, 2310040P19Rik antikoerper, AL024030 antikoerper, mHR23A antikoerper, RAD23 homolog A, nucleotide excision repair protein a antikoerper, RAD23 homolog A, nucleotide excision repair protein antikoerper, rad23aa antikoerper, RAD23A antikoerper, Rad23a antikoerper

Hintergrund: HR23A (also known as UV excision repair protein RAD23 homolog A) is one of two human homologs of Saccharomyces cerevisiae Rad23 (hHR23A and hHR23B), a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Synonyms: hHR 23A antibody, MGC111083 antibody, RAD23 homolog A antibody, RAD23 yeast homolog A antibody, RAD23a antibody

Gen-ID: 5886, 4826964

UniProt: P54725

Pathways: DNA Reparatur