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SFRP1 Antikörper

Rockland 600-401-475 SFRP1 Reaktivität: Human WB, IHC, ELISA, FM Wirt: Kaninchen Polyclonal unconjugated
Rockland
Produktnummer ABIN129592
Hersteller Produkt- Nr.: 600-401-475
  • Target Alle SFRP1 Antikörper anzeigen
    SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
    Reaktivität
    • 41
    • 34
    • 33
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 54
    • 9
    • 2
    • 2
    Kaninchen
    Klonalität
    • 56
    • 11
    Polyklonal
    Konjugat
    • 27
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SFRP1 Antikörper ist unkonjugiert
    Applikation
    • 52
    • 22
    • 21
    • 13
    • 13
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Fluorescence Microscopy (FM)
    Hersteller Produkt- Nr.
    600-401-475
    Hersteller
    Rockland
    Verwendungszweck
    SFRP1 Antibody
    Kreuzreaktivität (Details)
    This affinity purified antibody is directed against human SFRP protein.
    Produktmerkmale
    Synonyms: rabbit anti-SFRP1 antibody, SFRP-1, secreted frizzled related protein 1 antibody, FRP-1 antibody, FRP 1 antibody, FRP1 antibody, FrzA antibody, SARP 2 antibody, SARP2 antibody, Secreted Apoptosis-related Protein 2 antibody
    Aufreinigung
    The product was affinity purified from monospecific antiserum by immunoaffinity purification.
    Sterilität
    Sterile filtered
    Immunogen

    Immunogen: SFRP1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a 12 aa region of human Sfrp1 protein.

    Immunogen Type: Conjugated Peptide

    Isotyp
    IgG
    Top Product
    Discover our top product SFRP1 Primärantikörper
  • Applikationshinweise

    Immunohistochemistry Dilution: 1:800

    Application Note: This affinity purified antibody has been tested for use in ELISA, western blot, and IHC.  This antibody is suitable for immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 37 kDa in size corresponding to Sfrp1 by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:200-1:2,000

    ELISA Dilution: 1:5,000 - 1:15,000

    IF Microscopy Dilution: Use at a concentration of 5 μg/mL

    Other: User Optimized

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Huang, Zhang, Teng, Lin, Zheng, Yang, Han: "Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma." in: BMC cancer, Vol. 7, pp. 126, (2007) (PubMed).

    Garcia-Hoyos, Cantalapiedra, Arroyo, Esteve, Rodríguez, Riveiro, Trujillo, Ramos, Bovolenta, Ayuso: "Evaluation of SFRP1 as a candidate for human retinal dystrophies." in: Molecular vision, Vol. 10, pp. 426-31, (2004) (PubMed).

    Han, Amar: "Secreted frizzled-related protein 1 (SFRP1) protects fibroblasts from ceramide-induced apoptosis." in: The Journal of biological chemistry, Vol. 279, Issue 4, pp. 2832-40, (2004) (PubMed).

  • Target
    SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
    Andere Bezeichnung
    SFRP1 (SFRP1 Produkte)
    Hintergrund
    Background: Anti-SFRP1 is a Stem Cell Antibody. SFRP1 (also known as FRP, FRP1, SARP2, Secreted Apoptosis-related Protein 2, Secreted Frizzled-related Protein and Secreted frizzled-related protein 1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP1 is expressed in several human tissues, with the highest levels in heart.
    Gen-ID
    6422, 56117838
    UniProt
    Q8N474
    Pathways
    WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
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