PNKP Antikörper (Internal Region)

Produktnummer ABIN129595

Produktdetails anti-PNKP Antikörper

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNKP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Schimpanse

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an of human PNK protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 57 kDa in size corresponding to PNK by western blotting in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.46 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu PNKP

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Andere Bezeichnung: PNK (PNKP Produkte)

Synonyme: EIEE10 antikoerper, MCSZ antikoerper, PNK antikoerper, Tb06.28P18.320 antikoerper, 21.m03011 antikoerper, 1810009G08Rik antikoerper, polynucleotide kinase 3'-phosphatase antikoerper, hypothetical protein antikoerper, polynucleotide kinase 3'- phosphatase antikoerper, PNKP antikoerper, Pnkp antikoerper, Tc00.1047053507017.50 antikoerper, Tc00.1047053505807.190 antikoerper, Tb927.6.1580 antikoerper, BBOV_IV000690 antikoerper, CC1G_05202 antikoerper, PGTG_20262 antikoerper, PGTG_18987 antikoerper, pnkp.S antikoerper, pnkp antikoerper

Hintergrund: Mammalian PNK (also known as PNKP, Polynucleotide kinase 3'-phosphatase, DNA 5'-kinase/3'-phosphatase and Polynucleotide kinase) catalyzes the 5’ phosphorylation of nucleic acids and can have associated 3’ phosphatase activity, predictive of an important function in DNA repair following ionizing radiation or oxidative damage.  PNK is a nuclear protein that is expressed in many tissues with highest expression in spleen and testis, and lowest expression in small intestine.
Synonyms: Mammalian PNK, PNKP, Polynucleotide kinase 3'-phosphatase, DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase

Gen-ID: 11284, 31543419

UniProt: Q96T60

Pathways: DNA Reparatur, Nucleotide Phosphorylation