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IBTK Antikörper (Internal Region)

Rockland 600-401-486 IBTK Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Rockland
Produktnummer ABIN129599
Hersteller Produkt- Nr.: 600-401-486
  • Target Alle IBTK Antikörper anzeigen
    IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
    Bindungsspezifität
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    Human
    Wirt
    • 14
    • 2
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IBTK Antikörper ist unkonjugiert
    Applikation
    • 15
    • 10
    • 9
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Hersteller Produkt- Nr.
    600-401-486
    Hersteller
    Rockland
    Verwendungszweck
    BTB1 Antibody
    Produktmerkmale
    Synonyms: rabbit anti-BTB1 Antibody, BTB-1, BTB 1, IBTK, BTKI, Inhibitor of Bruton tyrosine kinase, BTK Binding Protein antibody
    Aufreinigung
    This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.
    Sterilität
    Sterile filtered
    Immunogen

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of Human Btb1. Btb1 is a currently uncharacterized human ankyrin repeat protein BAA92655. This protein has been suggested to bind to CUL3.

    Immunogen Type: Conjugated Peptide

    Isotyp
    IgG
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  • Applikationshinweise

    Application Note: This affinity purified antibody has been tested for use in ELISA against the immunizing peptide.  Reactivity in other immunoassays is unknown.

    Western Blot Dilution: 1:500 - 1:3,000

    ELISA Dilution: 1:5,000 - 1:25,000

    Other: User Optimized

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.63 mg/mL
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Target
    IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
    Andere Bezeichnung
    IBTK (IBTK Produkte)
    Hintergrund
    Background: BTB1 acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. It down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription.
    Gen-ID
    25998
    NCBI Accession
    NP_001287835
    UniProt
    Q9P2D0
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