Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Kreuzreaktivität
Schimpanse
Produktmerkmale
Concentration Definition: by UV absorbance at 280 nm
Immunogen
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 1-12 of human FANCG protein.
This affinity purified antibody has been tested for use in ELISA, immunohistochemistry and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 69 kDa in size corresponding to FANCG by western blotting in the appropriate human tissue.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.93 mg/mL
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Target
FANCG
(Fanconi Anemia Complementation Group G (FANCG))
xFANCG antikoerper, FAG antikoerper, XRCC9 antikoerper, AU041407 antikoerper, Xrcc9 antikoerper, Fanconi anemia complementation group G S homeolog antikoerper, Fanconi anemia complementation group G antikoerper, Fanconi anemia, complementation group G antikoerper, fancg.S antikoerper, FANCG antikoerper, Fancg antikoerper
Hintergrund
FANCG (also called Protein FACG or DNA-repair protein XRCC9) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCG may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. This protein may also function as a tumor suppressor gene. FANCG belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. FANCG is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is highly expressed in testis and thymus and is also found in lymphoblasts. Fanconi anemia is an Synonyms: DNA repair protein XRCC9 antibody, DNA-repair protein XRCC9 antibody, FAG antibody, Fanconi anaemia complementation group G antibody, Protein FACG antibody