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WRNIP1 Antikörper (Internal Region)

Rockland 600-401-676 WRNIP1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Rockland
Produktnummer ABIN129611
Hersteller Produkt- Nr.: 600-401-676
  • Target Alle WRNIP1 Antikörper anzeigen
    WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
    Bindungsspezifität
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    Internal Region
    Reaktivität
    • 20
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 19
    • 1
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser WRNIP1 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 10
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Hersteller Produkt- Nr.
    600-401-676
    Hersteller
    Rockland
    Verwendungszweck
    WHIP Antibody
    Kreuzreaktivität (Details)
    Reactivity is expected against human, mouse, rat and monkey WHIP1 protein.
    Produktmerkmale
    Synonyms: rabbit anti-WHIP antibody, ATPase WRNIP 1 antibody, ATPase WRNIP1 antibody, Werner helicasae interacting protein 1 antibody, WRNIP-1
    Aufreinigung
    This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide immobilized to a solid phase.
    Sterilität
    Sterile filtered
    Immunogen

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of the WHIP1 protein.  The immunogen sequence shows 100% homology to human WHIP1 (isoform 1) and WHIP2 (isoform 2) with predicted molecular weights of 72.2 kDa and 69.5 kDa, respectively.  The immunogen sequence also shows 100% homology to WHIP1 from mouse, rat and monkey sequences.  Reactivity with WHIP proteins from other sources is not known, but is likely due to reported homologies.

    Immunogen Type: Conjugated Peptide

    Isotyp
    IgG
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  • Applikationshinweise

    Immunohistochemistry Dilution: User Optimized

    Application Note: This affinity purified antibody has been tested by WB and ELISA. Anti-WHIP is useful in western blotting against HEK293 whole cell lysates.  Dilutions for western blotting represent a starting point dilution and further optimization may be required.  The antibody detects a band of approximately 96.0 kDa (predicted molecular weight: 72.2 kDa). Specific band detection by western blot is blocked by pre-incubating the antibody with the immunizing peptide prior to reaction with the membrane.  Reactivity in other immunoassays is unknown.

    Western Blot Dilution: 1:500 - 1:2,000

    ELISA Dilution: 1:10,000 - 1:40,000

    Other: User Optimized

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.10 mg/mL
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Target
    WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
    Andere Bezeichnung
    WRNIP1 (WRNIP1 Produkte)
    Hintergrund
    Background: Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging.  Werner helicase interacting protein 1 (WHIP) interacts with the N-terminal portion of Werner protein, which contains an exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene product may influence the aging process.  A second isoform exists (WHIP2).
    Gen-ID
    56897, 55661735
    UniProt
    Q96S55
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