ZIC2 Antikörper (AA 189-206)

Produktnummer ABIN129629

Produktdetails anti-ZIC2 Antikörper

Target: ZIC2

Bindungsspezifität: AA 189-206

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZIC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Schimpanse, Maus, Ratte (Rattus), Hund

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding amino acids 189-206 of Mouse ZIC-2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 55 kDa in size corresponding to ZIC2 by western blotting in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu ZIC2

Target: ZIC2

Andere Bezeichnung: ZIC-2 (ZIC2 Produkte)

Hintergrund: ZIC2 (also known as zinc finger protein of the cerebellum 2, HPE5, Zic family member 2 and odd-paired Drosophila homolog) is a nuclear protein that functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.
Synonyms: ZIC2, zinc finger protein of the cerebellum 2, HPE5, Zic family member 2 and odd-paired Drosophila homolog

Gen-ID: 7546, 22547197

UniProt: O95409

Pathways: Tube Formation