LIM Domain Kinase 1 Antikörper (AA 630-647)

Produktnummer ABIN129635

Produktdetails anti-LIM Domain Kinase 1 Antikörper

Target: LIM Domain Kinase 1 (LIMK1)

Bindungsspezifität: AA 630-647

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIM Domain Kinase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Schimpanse, Orang-Utan

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 630-647 of human LIM kinase protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 73 kDa in size corresponding to LIM kinase by western blotting in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu LIM Domain Kinase 1

Target: LIM Domain Kinase 1 (LIMK1)

Andere Bezeichnung: LIM Kinase (LIMK1 Produkte)

Synonyme: limk1 antikoerper, xlimk1 antikoerper, GB16654 antikoerper, LIMK1 antikoerper, LIMK antikoerper, LIMK-1 antikoerper, LIM domain kinase 1 antikoerper, LIM domain kinase 1a antikoerper, LIM domain kinase 1 L homeolog antikoerper, LIM-domain containing, protein kinase antikoerper, LIMK1 antikoerper, limk1a antikoerper, limk1 antikoerper, CpipJ_CPIJ000717 antikoerper, LOC413152 antikoerper, Limk1 antikoerper, limk1.L antikoerper

Hintergrund: LIM Kinase is also known as LIM-domain containing protein kinase, LIMK-1 and LIMK.  There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is
Synonyms: LIM domain kinase 1 antibody, LIMK1 antibody

Gen-ID: 3984, 4505001

UniProt: P53667

Pathways: Caspase Kaskade in der Apoptose, Regulation of Cell Size, CXCR4-mediated Signaling Events