DLL1 Antikörper (AA 155-173)

Produktnummer ABIN129638

Produktdetails anti-DLL1 Antikörper

Target: DLL1 (delta-Like 1 (DLL1))

Bindungsspezifität: AA 155-173

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Ratte (Rattus), Human, Huhn

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 155-173 of Mouse DELTA-1. DELTA-1 is a mouse homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. Swiss Prot accession Q61483. Expected to cross-react with rat, human and chicken.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Anti-DELTA-1 Antibody has been tested for use in ELISA against the immunizing peptide.  It is expected that anti-Delta-1 antibody will be reactive in western blot assays Reactivity in other immunoassays is unknown.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-DLL1 Antikörper (ABIN129638)

Meliou, Kerezoudis, Tosios, Kiaris: "Notch 1 Receptor, Delta 1 Ligand and HES 1 Transcription Factor are Expressed in the Lining Epithelium of Periapical Cysts (Preliminary Study)." in: The open dentistry journal, Vol. 4, pp. 153-8, (2011) (PubMed).

Zhang, Zeng, Zhang, Jiao, Li, Jing, Ouyang, Yuan, Chai, Che, Zhang, Yang: "Suppressor of cytokine signaling 3 promotes bone marrow cells to differentiate into CD8+ T lymphocytes in lung tissue via up-regulating Notch1 expression." in: Cancer research, Vol. 69, Issue 4, pp. 1578-86, (2009) (PubMed).

Details zu DLL1

Target: DLL1 (delta-Like 1 (DLL1))

Andere Bezeichnung: DELTA-1 (DLL1 Produkte)

Synonyme: X-delta-1 antikoerper, XDelta1 antikoerper, Xdelta-1 antikoerper, delta antikoerper, delta-1 antikoerper, delta1 antikoerper, x-delta antikoerper, DELTA1 antikoerper, DL1 antikoerper, Delta antikoerper, DLK antikoerper, DLK-1 antikoerper, Delta1 antikoerper, FA1 antikoerper, PREF1 antikoerper, Pref-1 antikoerper, ZOG antikoerper, pG2 antikoerper, DLL1 antikoerper, AW742678 antikoerper, DlkI antikoerper, Ly107 antikoerper, Peg9 antikoerper, SCP1 antikoerper, pref-1 antikoerper, delta-like 1 antikoerper, delta like canonical Notch ligand 1 antikoerper, delta like non-canonical Notch ligand 1 antikoerper, delta-like 1 L homeolog antikoerper, delta-like 1 (Drosophila) antikoerper, delta-like 1 homolog (Drosophila) antikoerper, dll1 antikoerper, DLL1 antikoerper, DLK1 antikoerper, Dll1 antikoerper, dll1.L antikoerper, Dlk1 antikoerper

Hintergrund: Delta-like protein 1 is a protein that in humans is encoded by the DLL1 gene. The Notch signaling pathway has pleiotropic functions during mammalian embryogenesis. It is required for the patterning and differentiation of the presomitic and somitic paraxial mesoderm and of the neural tube. DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis, and has been shown to have a role in cell-to-cell communication. Anti-Delta-like protein 1 antibody would be sutiable for researchers in Cell Biology and Signal Transduction.
Synonyms: Delta-like protein 1 antibody, Drosophila Delta homolog 1 antibody

Gen-ID: 13388

UniProt: Q61483

Pathways: Notch Signalweg, Stem Cell Maintenance