SLIT1 Antikörper (AA 487-504)

Produktnummer ABIN129640

Produktdetails anti-SLIT1 Antikörper

Target: SLIT1 (Slit Homolog 1 (SLIT1))

Bindungsspezifität: AA 487-504

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLIT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Ratte (Rattus)

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 487-504 of mouse SLIT-1 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect multiple bands corresponding to cleavage products of SLIT-1 by western blotting in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.2 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu SLIT1

Target: SLIT1 (Slit Homolog 1 (SLIT1))

Andere Bezeichnung: SLIT-1 (SLIT1 Produkte)

Synonyme: Slil1 antikoerper, mKIAA0813 antikoerper, MEGF4 antikoerper, SLIL1 antikoerper, SLIT-1 antikoerper, SLIT3 antikoerper, megf4 antikoerper, slil1 antikoerper, slit-1 antikoerper, SLIT1 antikoerper, slit3 antikoerper, slit homolog 1 (Drosophila) antikoerper, slit guidance ligand 1 antikoerper, slit guidance ligand 1 S homeolog antikoerper, slit homolog 1 protein antikoerper, slit homolog 1b (Drosophila) antikoerper, slit homolog 1a (Drosophila) antikoerper, Slit1 antikoerper, SLIT1 antikoerper, slit1.S antikoerper, slit1 antikoerper, LOC100459557 antikoerper, slit1b antikoerper, slit1a antikoerper

Hintergrund: SLIT-1 (also known as KIAA0813, MEGF4, multiple epidermal growth factor-like domains 4 and Slit homolog 1 protein) is a Slit protein.  This protein is a ligand for the Roundabout (Robo) receptors and acts as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb.  Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. In situ hybridization studies indicated that the rat SLIT-1 mRNA was specifically expressed in the neurons of fetal and adult forebrains. This data suggests that the SLIT genes form an evolutionarily conserved group in vertebrates and invertebrates, and that the mammalian SLIT proteins may participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions.  Alternative splicing isoforms have been identified for Slit1 protein.
Synonyms: KIAA0813 antibody, MEGF 4 antibody, MEGF4 antibody, Multiple epidermal growth factor-like domains 4 antibody

Gen-ID: 20562, 256355216

UniProt: Q80TR4

Pathways: Regulation of Cell Size