CAMK2A Antikörper (AA 6-23)

Produktnummer ABIN129648

Produktdetails anti-CAMK2A Antikörper

Target: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Bindungsspezifität: AA 6-23

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAMK2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Maus, Ratte (Rattus), Hund, Orang-Utan

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 6-23 of Human CaM Kinase II protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 54 kDa in size corresponding to CaM Kinase II by western blotting in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.57 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu CAMK2A

Target: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Andere Bezeichnung: CaM Kinase II (CAMK2A Produkte)

Synonyme: camk2 antikoerper, camk2b antikoerper, zgc:112538 antikoerper, zgc:123320 antikoerper, CAMKA antikoerper, CaMKII antikoerper, R74975 antikoerper, mKIAA0968 antikoerper, PK2CDD antikoerper, PKCCD antikoerper, calcium/calmodulin dependent protein kinase II alpha antikoerper, calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog antikoerper, calcium/calmodulin-dependent protein kinase II alpha antikoerper, CAMK2A antikoerper, camk2a.S antikoerper, camk2a antikoerper, Camk2a antikoerper

Hintergrund: CaM Kinase II (also known as CAMK2 and calcium/calmodulin-dependent protein kinase type II alpha chain) is a prominent kinase in the central nervous system that may function in the long-term potentiation of neurotransmitter release.  CaM Kinase II autophosphorylates itself at Thr-286 which allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CaM Kinase II is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. This kinase is expressed in brain tissue.  Alternative splicing occurs for this gene product.
Synonyms: Calcium/calmodulin dependent protein kinase II alpha antibody, CaM kinase II alpha antibody, CaM kinase II alpha chain antibody, CaM kinase II alpha subunit antibody, CaM kinase II antibody, CaM kinase II beta antibody

Gen-ID: 25400, 125285

UniProt: P11275

Pathways: WNT Signalweg, Interferon-gamma Pathway, Myometrial Relaxation and Contraction