GPX4 Antikörper (C-Term)

Produktnummer ABIN129715

Produktdetails anti-GPX4 Antikörper

Target: GPX4 (Glutathione Peroxidase 4 (GPX4))

Bindungsspezifität: C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Ratte (Rattus), Meerschweinchen

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the of mouse GPx4 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 19 kDa in size corresponding to GPx4 protein by western blotting in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.15 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu GPX4

Target: GPX4 (Glutathione Peroxidase 4 (GPX4))

Abstract: GPX4 Produkte

Synonyme: GPx-4 antikoerper, GSHPx-4 antikoerper, MCSP antikoerper, PHGPx antikoerper, snGPx antikoerper, snPHGPx antikoerper, Phgpx antikoerper, gpx-4 antikoerper, snGpx antikoerper, cb563 antikoerper, cb691 antikoerper, PHGPxa antikoerper, sb:cb563 antikoerper, zgc:92253 antikoerper, wu:fb82e03 antikoerper, 1700027O09Rik antikoerper, mtPHGPx antikoerper, ATGPX4 antikoerper, F11L15.5 antikoerper, glutathione peroxidase 4 antikoerper, GP-GPx4 antikoerper, glutathione peroxidase 4 antikoerper, glutathione peroxidase 4a antikoerper, GPX4 antikoerper, Gpx4 antikoerper, gpx4a antikoerper

Hintergrund: This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Glutathione Peroxidase 4 (GPx4, also known as PHGPx) functions as an antioxidant and also plays a role in redox regulation, sexual maturation, inflammation, apoptosis, and differentiation.  GPx4 was found to have an important role in preventing lipid peroxidation, and has been discussed primarily as the glutathione peroxidase protecting biomembranes against oxidative stress.  GPx4 can react with free hydrogen peroxide as well as with a wide range of lipid hydroperoxides, including those derived from cholesterol and cholesteryl esters.  GPx4 is the only GPx to use phospholipid hydroperoxides as substrates.  It can also reduce thymine hydroperoxide. In contrast to GPx1 and GPx3, GPx4 can use a wide range of reducing substrates in addition to glutathione.  GPx4 is expressed in high levels in testes, suggesting a role in male fertility.  It has also been identified as an enzymatically inactive structural protein of the mitochondrial capsule of sperm.
Synonyms: GPX4 antibody, MCSP antibody, PHGPx antibody, Phospholipid hydroperoxidase antibody, Phospholipid hydroperoxide glutathione peroxidase antibody

Gen-ID: 625249, 13508533

UniProt: O70325