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DC-SIGN/CD209 Antikörper

CD209 Reaktivität: Human FACS, IHC, ICC Wirt: Maus Monoclonal UW60-1 unconjugated
Produktnummer ABIN1302458
  • Target Alle DC-SIGN/CD209 (CD209) Antikörper anzeigen
    DC-SIGN/CD209 (CD209) (CD209)
    Reaktivität
    • 101
    • 27
    • 22
    • 1
    • 1
    Human
    Wirt
    • 70
    • 44
    • 4
    • 1
    Maus
    Klonalität
    • 69
    • 50
    Monoklonal
    Konjugat
    • 57
    • 9
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert
    Applikation
    • 68
    • 50
    • 31
    • 28
    • 28
    • 13
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Spezifität
    The mouse monoclonal antibody UW60.1 recognizes an extracellular epitope of human CD209 (DC-SIGN), a 44 kDa transmembrane receptor, expressed on the surface of dendritic cells and macrophages.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    CD209-His-tagged fusion protein
    Klon
    UW60-1
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD209 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Ryan, Marshall, Magaletti, Floyd, Draves, Olson, Clark: "Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 10, pp. 5638-48, (2002) (PubMed).

  • Target
    DC-SIGN/CD209 (CD209) (CD209)
    Andere Bezeichnung
    CD209 (CD209 Produkte)
    Hintergrund
    CD209 Molecule,CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).,CLEC4L, DC-SIGN1, CDSIGN
    Gen-ID
    30835
    UniProt
    Q9NNX6
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