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Lambda-IgLC Antikörper (APC)

Lambda-IgLC Reaktivität: Human FACS Wirt: Maus Monoclonal 1-155-2 APC
Produktnummer ABIN1302655
  • Target Alle Lambda-IgLC Produkte
    Lambda-IgLC (lambda Light Chain (Lambda-IgLC))
    Reaktivität
    • 26
    • 15
    Human
    Wirt
    • 22
    • 18
    • 1
    Maus
    Klonalität
    • 22
    • 19
    Monoklonal
    Konjugat
    • 10
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Lambda-IgLC Antikörper ist konjugiert mit APC
    Applikation
    • 19
    • 15
    • 13
    • 13
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody 1-155-2 recognizes lambda light chains (22.5 kDa) of human immunoglobulin.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    Human IgA1 lambda myeloma protein
    Klon
    1-155-2
    Isotyp
    IgG1 kappa
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Extracellular and intracellular staining.
    Kommentare

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Avoid prolonged exposure to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Tierens, Holte, Warsame, Ikonomou, Wang, Chan, Delabie: "Low levels of monoclonal small B cells in the bone marrow of patients with diffuse large B-cell lymphoma of activated B-cell type but not of germinal center B-cell type." in: Haematologica, Vol. 95, Issue 8, pp. 1334-41, (2010) (PubMed).

    Bahler, Pindzola, Swerdlow: "Splenic marginal zone lymphomas appear to originate from different B cell types." in: The American journal of pathology, Vol. 161, Issue 1, pp. 81-8, (2002) (PubMed).

    Kubagawa, Gathings, Levitt, Kearney, Cooper: "Immunoglobulin isotype expression of normal pre-B cells as determined by immunofluorescence." in: Journal of clinical immunology, Vol. 2, Issue 4, pp. 264-9, (1983) (PubMed).

  • Target
    Lambda-IgLC (lambda Light Chain (Lambda-IgLC))
    Andere Bezeichnung
    Lambda light chains (Lambda-IgLC Produkte)
    Hintergrund
    Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.,Immunoglobulin lambda, Igl
    Molekulargewicht
    22.5 kDa
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