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HMGB1 Antikörper (AA 1-215)

Name: HMGB1 Antikörper (AA 1-215)
SKU: ABIN1326935
Price: 661.92 EUR
Availability: InStock

HMGB1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1E6-E10 unconjugated

Western Blot analysis of HMGB1 expression in transfected 293T cell line by HMGB1 monoclonal antibody (M01), clone 1E6-E10. (HMGB1 Antikörper (AA 1-215))

Immunoperoxidase of monoclonal antibody to HMGB1 on formalin-fixed paraffin-embedded human stomach. (HMGB1 Antikörper (AA 1-215))

ISt

Immunofluorescence of monoclonal antibody to HMGB1 on HeLa cell. (HMGB1 Antikörper (AA 1-215))

Detection limit for recombinant GST tagged HMGB1 is 0. (HMGB1 Antikörper (AA 1-215))

ELISA

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN1326935

Datenblatt (PDF)

Target Alle HMGB1 Antikörper anzeigen

HMGB1 (High Mobility Group Box 1 (HMGB1))
Bindungsspezifität
21

16

16

9

8

6

6

6

4

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-215
Reaktivität
155

94

93

13

11

11

10

8

7

6

6

6

5

2

1

1

1
Human
Wirt
132

32

2

2

2

1
Maus
Passende Sekundärantikörper
Klonalität
122

49
Monoklonal
Konjugat
85

17

16

7

5

5

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1
Dieser HMGB1 Antikörper ist unkonjugiert
Applikation
134

57

50

47

30

29

27

26

21

10

9

5

2

2

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck

Mouse monoclonal antibody raised against a full-length recombinant HMGB1.

Sequenz

MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEED EEDEEDEEEE EDEEDEDEEE DDDDE

Kreuzreaktivität

Human

Produktmerkmale

Antibody Reactive Against Recombinant Protein.

Immunogen

HMGB1 (AAH03378.1, 1 a.a. ~ 215 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon

1E6-E10

Isotyp

IgG1

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HMGB1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

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HMGB1 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

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HMGB1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-High Mobility Group Box 1 (HMGB1) (AA 1-215) antibody
HMGB1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal 1# unconjugated

anti-High Mobility Group Box 1 (HMGB1) (N-Term) antibody
HMGB1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

In 1x PBS, pH 7.4

Handhabung

Aliquot to avoid repeated freezing and thawing.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Kim, Ku, Bae: "Persicarin is anti-inflammatory mediator against HMGB1-induced inflammatory responses in HUVECs and in CLP-induced sepsis mice." in: Journal of cellular physiology, Vol. 228, Issue 4, pp. 696-703, (2013) (PubMed).

Lee, Ku, Kim, Bae: "Emodin-6-O-?-D-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 52, pp. 97-104, (2013) (PubMed).
Target

HMGB1 (High Mobility Group Box 1 (HMGB1))

Andere Bezeichnung

HMGB1 (HMGB1 Produkte)

Hintergrund

Full Gene Name: high-mobility group box 1
Synonyms: DKFZp686A04236,HMG1,HMG3,SBP-1

Gen-ID

3146

Pathways

p53 Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome