BCL2L1 Antikörper
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- Target Alle BCL2L1 Antikörper anzeigen
- BCL2L1 (BCL2-Like 1 (BCL2L1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser BCL2L1 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- Human/Mouse/Rat/Rhesus Bcl-xL
- Produktmerkmale
- Mouse Anti-Bcl-xL-UNLB
- Aufreinigung
- Purified
- Immunogen
- Recombinant human Bcl-xS
- Klon
- 7B2-5
- Isotyp
- IgG3
- Top Product
- Discover our top product BCL2L1 Primärantikörper
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- Applikationshinweise
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- Applications: FC - Quality tested , IHC-PS - Reported in literature , ICC - Reported in literature , WB - Reported in literature , IP - Reported in literature , ELISA - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 3 g/106 cells PE conjugate 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L Immunoblotting Purified (UNLB) antibody 1 g/mL
- Probenmenge
- 1 mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/mL
- Buffer
- 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
- Konservierungsmittel
- Without preservative
- Handhabung
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C
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The ability of Bcl-x(L) and Bcl-2 to prevent apoptosis can be differentially regulated." in: Cell death and differentiation, Vol. 3, Issue 1, pp. 113-8, (2006) (PubMed).
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The ability of Bcl-x(L) and Bcl-2 to prevent apoptosis can be differentially regulated." in: Cell death and differentiation, Vol. 3, Issue 1, pp. 113-8, (2006) (PubMed).
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- Target
- BCL2L1 (BCL2-Like 1 (BCL2L1))
- Andere Bezeichnung
- Bcl-xL (BCL2L1 Produkte)
- Synonyme
- BCL-XL/S antikoerper, BCL2L antikoerper, BCLX antikoerper, BCLXL antikoerper, BCLXS antikoerper, Bcl-X antikoerper, PPP1R52 antikoerper, bcl-xL antikoerper, bcl-xS antikoerper, Bcl(X)L antikoerper, Bcl-XL antikoerper, Bcl-Xs antikoerper, Bcl2l antikoerper, BclX antikoerper, bcl-x antikoerper, Bcl-xl antikoerper, Bclx antikoerper, bcl-X antikoerper, Bcl-xL antikoerper, BCL-XL antikoerper, BCL2L1 antikoerper, bcl-XL antikoerper, bcl-x(l) antikoerper, bcl-xl/s antikoerper, bcl-xs antikoerper, bcl2l antikoerper, bclx antikoerper, bclxl antikoerper, xR11 antikoerper, bcl-xl antikoerper, blp1 antikoerper, cb1021 antikoerper, zfBLP1 antikoerper, BCL2 like 1 antikoerper, BCL2-like 1 antikoerper, Bcl2-like 1 antikoerper, BCL2-like 1 L homeolog antikoerper, bcl2-like 1 antikoerper, BCL2L1 antikoerper, Bcl2l1 antikoerper, bcl2l1 antikoerper, bcl2l1.L antikoerper
- Hintergrund
- Apoptosis, or programmed cell death, is a well-documented phenomenon in many cellular systems. It plays a key role in tissue and organ development as well as in adult tissues during cell turnover. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment. Bcl-2 and one of its homologues, Bcl-xL, protect cells from apoptosis, while other homologues of Bcl-2 such as Bax, Bad and Bak have been shown to enhance apoptosis. Bcl-xL has been shown to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. In contrast, Bad and Bax inhibit the protective functions of Bcl-xL and Bcl-2, respectively. Although heterodimerization between Bcl-xL/Bad and Bcl-2/Bax was originally thought to be essential for the differential anti-apoptotic activity of Bcl-xL and Bcl-2, other results suggest that the formation of heterodimers may not be necessary for this death-repressing activity.
- Pathways
- Apoptose, Negative Regulation of intrinsic apoptotic Signaling
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