Collagen IV Antikörper

Produktnummer ABIN135052

Produktdetails anti-Collagen IV Antikörper

Target: Collagen IV (COL4) (Collagen, Type IV (COL4))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Collagen IV Antikörper ist unkonjugiert

Applikation: ELISA

Spezifität: Reacts with conformational determinants on type IV collagen Referenced species reactivities include - Human 1,12,14,27,29,31,34,36 Chicken 5,13,15 Porcine 11,22,25 Mouse 4,5,7,8,30,32 Chinchilla 17 Rabbit 5,6,14,20,23 Rat 2,3,10,26,27,33,35 Equine 18,28 Sheep 24 Bovine 5,24 Guinea Pig 14 Tree Shrew 21 Canine 9,19 Japanese Macaque 16

Kreuzreaktivität (Details): Exhibits < 10 % cross reactivity with collagen type II, III, IV, V and VI. The antibody has not been tested for reactivity with other ECM proteins (e.g., laminin, fibronectin).

Produktmerkmale: Goat Anti-Type IV Collagen-UNLB

Aufreinigung: Purification Method: Affinity chromatography on type IV collagen covalently linked to agarose.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

• Applications: Quality tested applications include - ELISA , FLISA
• Other referenced applications include - IHC-PS , IHC-FS , ICC , EM , FC , WB , IP
• Working Dilutions: ELISA BIOT conjugate 1:1,000 - 1:4,000 FLISA AF488 conjugate 1:200 - 1:400

Probenmenge: 0,5 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.4 mg/mL

Buffer: 0.2 mg of purified immunoglobulin in 0.5 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Konservierungsmittel: Without preservative

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Referenzen für anti-Collagen IV Antikörper (ABIN135052)

Tonello, Lee, Berta: "Monoclonal Antibody Targeting the Matrix Metalloproteinase 9 Prevents and Reverses Paclitaxel-Induced Peripheral Neuropathy in Mice." in: The journal of pain : official journal of the American Pain Society, Vol. 20, Issue 5, pp. 515-527, (2020) (PubMed).

Zaitoun, Cikla, Zafer, Udho, Almomani, Suscha, Cengiz, Sorenson, Sheibani: "Attenuation of Retinal Vascular Development in Neonatal Mice Subjected to Hypoxic-Ischemic Encephalopathy." in: Scientific reports, Vol. 8, Issue 1, pp. 9166, (2019) (PubMed).

Singh, Houng, Reed: "Matrix Metalloproteinase-9 Mediates the Deleterious Effects of α2-Antiplasmin on Blood-Brain Barrier Breakdown and Ischemic Brain Injury in Experimental Stroke." in: Neuroscience, Vol. 376, pp. 40-47, (2019) (PubMed).

Fisslthaler, Zippel, Abdel Malik, Delgado Lagos, Zukunft, Thoele, Siuda, Soehnlein, Wittig, Heidler, Weigert, Fleming: "Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis." in: International journal of molecular sciences, Vol. 20, Issue 12, (2019) (PubMed).

Dias, Kim, Holl, Werne Solnestam, Lundeberg, Carlén, Göritz, Frisén: "Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury." in: Cell, Vol. 173, Issue 1, pp. 153-165.e22, (2019) (PubMed).

Ellenbroek, de Haan, van Klarenbosch, Brans, van de Weg, Smeets, de Jong, Arslan, Timmers, Goumans, Hoefer, Doevendans, Pasterkamp, Meyaard, de Jager: "Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice." in: Scientific reports, Vol. 7, Issue 1, pp. 18039, (2019) (PubMed).

Hu, Dziumbla, Lin, Bibli, Zukunft, de Mos, Awwad, Frömel, Jungmann, Devraj, Cheng, Wang, Fauser, Eberhart, Sodhi, Hammock, Liebner, Müller, Glaubitz, Hammes, Popp, Fleming: "Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy." in: Nature, Vol. 552, Issue 7684, pp. 248-252, (2018) (PubMed).

Mao, Kiss, Ou, Gould: "Genetic dissection of anterior segment dysgenesis caused by a Col4a1 mutation in mouse." in: Disease models & mechanisms, Vol. 10, Issue 4, pp. 475-485, (2017) (PubMed).

Friedrich, Bederson, Sehba: "Gender influences the initial impact of subarachnoid hemorrhage: an experimental investigation." in: PLoS ONE, Vol. 8, Issue 11, pp. e80101, (2015) (PubMed).

Chen, Advani, Thai, Kabir, Sood, Gibson, Yuen, Connelly, Marsden, Kelly, Gilbert, Advani: "SDF-1/CXCR4 Signaling Preserves Microvascular Integrity and Renal Function in Chronic Kidney Disease." in: PLoS ONE, Vol. 9, Issue 3, pp. e92227, (2014) (PubMed).

Mao-Ying, Kavelaars, Krukowski, Huo, Zhou, Price, Cleeland, Heijnen: "The Anti-Diabetic Drug Metformin Protects against Chemotherapy-Induced Peripheral Neuropathy in a Mouse Model." in: PLoS ONE, Vol. 9, Issue 6, pp. e100701, (2014) (PubMed).

Wu, Davis, McMillen, Schaeffer, Zhou, Qi, Mazandarani, Alialy, Hudkins, Lusis, LeBoeuf: "Genetic modulation of diabetic nephropathy among mouse strains with Ins2 Akita mutation." in: Physiological reports, Vol. 2, Issue 11, (2014) (PubMed).

Abrahamson, St John, Stroganova, Zelenchuk, Steenhard: "Laminin and type IV collagen isoform substitutions occur in temporally and spatially distinct patterns in developing kidney glomerular basement membranes." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 61, Issue 10, pp. 706-18, (2013) (PubMed).

Maggi, Ericson, Mascarelli, Bradley, Breitschwerdt: "Bartonella henselae bacteremia in a mother and son potentially associated with tick exposure." in: Parasites & vectors, Vol. 6, pp. 101, (2013) (PubMed).

Mirmalek-Sani, Orlando, McQuilling, Pareta, Mack, Salvatori, Farney, Stratta, Atala, Opara, Soker: "Porcine pancreas extracellular matrix as a platform for endocrine pancreas bioengineering." in: Biomaterials, Vol. 34, Issue 22, pp. 5488-95, (2013) (PubMed).

Manigrasso, Sawyer, Hutchens, Flynn, Maric-Bilkan: "Combined inhibition of aromatase activity and dihydrotestosterone supplementation attenuates renal injury in male streptozotocin (STZ)-induced diabetic rats." in: American journal of physiology. Renal physiology, (2012) (PubMed).

Manigrasso, Sawyer, Marbury, Flynn, Maric: "Inhibition of estradiol synthesis attenuates renal injury in male streptozotocin-induced diabetic rats." in: American journal of physiology. Renal physiology, Vol. 301, Issue 3, pp. F634-40, (2011) (PubMed).

Boyette-Davis, Cata, Zhang, Driver, Wendelschafer-Crabb, Kennedy, Dougherty: "Follow-up psychophysical studies in bortezomib-related chemoneuropathy patients." in: The journal of pain : official journal of the American Pain Society, Vol. 12, Issue 9, pp. 1017-24, (2011) (PubMed).

Liu, Chen, Huang, Chung, Zhou, Fu, Szalai, Lan: "C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes." in: Diabetologia, Vol. 54, Issue 10, pp. 2713-23, (2011) (PubMed).

Glorieux, Bachert, Favoreel, Vandekerckhove, Steukers, Rekecki, Van den Broeck, Goossens, Croubels, Clayton, Nauwynck: "Herpes simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosa." in: PLoS ONE, Vol. 6, Issue 7, pp. e22160, (2011) (PubMed).

Details zu Collagen IV

Target: Collagen IV (COL4) (Collagen, Type IV (COL4))

Andere Bezeichnung: Type IV Collagen (COL4 Produkte)

Synonyme: collagen, type IV antikoerper, Let-2 antikoerper