Fibrillin Antikörper

Produktnummer ABIN135062

Produktdetails anti-Fibrillin Antikörper

Target: Fibrillin (FBL)

Reaktivität: Rind (Kuh), Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fibrillin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC)

Produktmerkmale: The antibody detects: Human and bovine fibrillin (Mr 350 kDa), other species not tested
In immunohistochemical staining of paraformaldehyde-fixed human skin, mAb 11C1.3 labels the elastic framework and more specifically the oxytalantic network close to the epidermis. The antibody also exhibits discrete staining of normal fibroblasts in culture and of extracellular (elastin) fibrils in a variety of tissues. There is an aberrant expression of fibrillin in Marfan syndrome.

Aufreinigung: Purified

Immunogen: Microfibrils from zonular apparatus of bovine eye Ig

Klon: 11C1-3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Working Dilution:
Immunohistochemistry: 1:50-1:100 (30-60 min at RT)
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Product is supplied as 0.2 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Details zu Fibrillin

Target: Fibrillin (FBL)

Andere Bezeichnung: Fibrillin (FBL Produkte)

Synonyme: T24H24.16 antikoerper, T24H24_16 antikoerper, fibrillin antikoerper, fibrillin antikoerper, hypothetical protein antikoerper, fibrillar structure forming protein antikoerper, FIB antikoerper, T26E3.6 antikoerper, ORF-18 p10 antikoerper

Hintergrund: The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear.