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CD44 Antikörper

CD44 Reaktivität: Maus FACS Wirt: Ratte Monoclonal KM201 unconjugated
Produktnummer ABIN135069
  • Target Alle CD44 Antikörper anzeigen
    CD44
    Reaktivität
    • 298
    • 154
    • 75
    • 32
    • 25
    • 22
    • 14
    • 13
    • 10
    • 9
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 179
    • 118
    • 91
    • 1
    • 1
    Ratte
    Klonalität
    • 283
    • 104
    • 3
    Monoklonal
    Konjugat
    • 179
    • 47
    • 32
    • 23
    • 18
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD44 Antikörper ist unkonjugiert
    Applikation
    • 292
    • 153
    • 93
    • 80
    • 72
    • 71
    • 60
    • 45
    • 40
    • 30
    • 28
    • 15
    • 9
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Mouse CD44 (all isoforms), Mr 80-95 kDa
    Produktmerkmale
    Rat Anti-Mouse CD44-LE/AF
    Endotoxin-Niveau
    Low endotoxin
    Immunogen
    (C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal clone BMS2
    Klon
    KM201
    Isotyp
    IgG1
    Top Product
    Discover our top product CD44 Primärantikörper
  • Applikationshinweise
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Kommentare

    cell adhesion and homing

    Probenmenge
    1 mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    Konservierungsmittel
    Azide free
    Handhabung
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • Target
    CD44
    Andere Bezeichnung
    CD44 (CD44 Produkte)
    Hintergrund
    CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte Cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.
    Pathways
    Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling
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