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CD3 epsilon Antikörper

CD3E Reaktivität: Maus FACS Wirt: Hamster Monoclonal 145-2C11 unconjugated
Produktnummer ABIN135085
  • Target Alle CD3 epsilon (CD3E) Antikörper anzeigen
    CD3 epsilon (CD3E)
    Reaktivität
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    Maus
    Wirt
    • 139
    • 125
    • 45
    • 23
    • 23
    • 10
    • 1
    • 1
    • 1
    Hamster
    Klonalität
    • 249
    • 112
    • 7
    Monoklonal
    Konjugat
    • 143
    • 33
    • 29
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    • 18
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    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    Dieser CD3 epsilon Antikörper ist unkonjugiert
    Applikation
    • 268
    • 149
    • 107
    • 86
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    • 69
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    Flow Cytometry (FACS)
    Spezifität
    Mouse CD3, Mr 25 kDa
    Produktmerkmale
    Hamster Anti-Mouse CD3e-UNLB
    Aufreinigung
    Purified
    Immunogen
    H-2Kb-specific murine cytotoxic T-lymphocyte (CTL) clone BM10-37
    Klon
    145-2C11
    Isotyp
    IgG
    Top Product
    Discover our top product CD3E Primärantikörper
  • Applikationshinweise
    • Applications: FC - Quality tested , IHC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature , Depletion - Reported in literature , Activ - Reported in literature , CMCD - Reported in literature
    • Working Dilutions: Flow Cytometry FITC conjugate 3 g/106 cells BIMA and AF488 conjugates 1 g/106 cells PE, APC, SPRD, and AF647 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 l
    Kommentare

    In vitro depletion of CD3+ cells, In vitro activation of T cells

    Probenmenge
    1 mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Konservierungsmittel
    Without preservative
    Handhabung
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C
  • Ershaid, Sharon, Doron, Raz, Shani, Cohen, Monteran, Leider-Trejo, Ben-Shmuel, Yassin, Gerlic, Ben-Baruch, Pasmanik-Chor, Apte, Erez: "NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis." in: Nature communications, Vol. 10, Issue 1, pp. 4375, (2020) (PubMed).

  • Target
    CD3 epsilon (CD3E)
    Andere Bezeichnung
    CD3e (CD3E Produkte)
    Hintergrund
    CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation.
    Pathways
    T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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