CD28 Antikörper (Biotin)
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- Target Alle CD28 Antikörper anzeigen
- CD28
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Reaktivität
- Maus
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Wirt
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Hamster
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD28 Antikörper ist konjugiert mit Biotin
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- Mouse CD28, Mr 40 kDa
- Produktmerkmale
- Hamster Anti-Mouse CD28-BIOT
- Immunogen
- C57BL/6N mouse T cell lymphoma EL-4 cell line
- Klon
- 37-51
- Isotyp
- IgG
- Top Product
- Discover our top product CD28 Primärantikörper
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- Applikationshinweise
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- Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Stim - Reported in literature , Activ - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Kommentare
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In vitro costimulation of T cells and NK cells
- Probenmenge
- 1 mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- 0.5 mg in 1.0 mL of PBS/Sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
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Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C
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- Target
- CD28
- Andere Bezeichnung
- CD28 (CD28 Produkte)
- Hintergrund
- CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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