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CD28 Antikörper

CD28 Reaktivität: Maus FACS Wirt: Hamster Monoclonal PV-1 unconjugated
Produktnummer ABIN135185
  • Target Alle CD28 Antikörper anzeigen
    CD28
    Reaktivität
    • 175
    • 127
    • 53
    • 37
    • 23
    • 16
    • 12
    • 12
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 156
    • 69
    • 33
    • 18
    • 12
    • 3
    • 2
    Hamster
    Klonalität
    • 225
    • 61
    • 4
    Monoklonal
    Konjugat
    • 110
    • 33
    • 30
    • 21
    • 16
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD28 Antikörper ist unkonjugiert
    Applikation
    • 227
    • 88
    • 61
    • 50
    • 39
    • 36
    • 34
    • 26
    • 23
    • 17
    • 13
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Mouse CD28, Mr 40 kDa
    Produktmerkmale
    Hamster Anti-Mouse CD28-UNLB
    Aufreinigung
    Purified
    Immunogen
    C57BL/6N mouse T cell lymphoma EL4 cell line
    Klon
    PV-1
    Isotyp
    IgG
    Top Product
    Discover our top product CD28 Primärantikörper
  • Applikationshinweise
    • Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Stim - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 3 g/106 cells PE, APC, and SPRD conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Kommentare

    In vitro costimulation of T cells and NK cells

    Probenmenge
    1 mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Konservierungsmittel
    Without preservative
    Handhabung
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C
  • Target
    CD28
    Andere Bezeichnung
    CD28 (CD28 Produkte)
    Hintergrund
    CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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