CD28 Antikörper
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- Target Alle CD28 Antikörper anzeigen
- CD28
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Reaktivität
- Maus
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Wirt
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Hamster
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD28 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- Mouse CD28, Mr 40 kDa
- Produktmerkmale
- Hamster Anti-Mouse CD28-LE/AF
- Endotoxin-Niveau
- Low endotoxin
- Immunogen
- C57BL/6N mouse T cell lymphoma EL4 cell line
- Klon
- PV-1
- Isotyp
- IgG
- Top Product
- Discover our top product CD28 Primärantikörper
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- Applikationshinweise
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- Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Stim - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 3 g/106 cells PE, APC, and SPRD conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Kommentare
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In vitro costimulation of T cells and NK cells
- Probenmenge
- 1 mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of PBS
- Konservierungsmittel
- Azide free
- Handhabung
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
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- Target
- CD28
- Andere Bezeichnung
- CD28 (CD28 Produkte)
- Hintergrund
- CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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