CD69 Antikörper (FITC)

Produktnummer ABIN135255

Produktdetails anti-CD69 Antikörper (FITC)

Target: CD69

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser CD69 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Spezifität: Mouse CD69, Mr 85 kDa (unreduced)

Produktmerkmale: Hamster Anti-Mouse CD69-FITC

Aufreinigung: Protein A

Immunogen: Mouse dendritic epidermal cell line Y245

Klon: H1-2F3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Costim - Reported in literature , Activ - Reported in literature
• Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE, APC, SPRD, PE/CY7, AF647, and PACBLU conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

In vitro T cell and NK-cell activation

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg in 1.0 mL of PBS/Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Referenzen für anti-CD69 Antikörper (FITC) (ABIN135255)

Waaler, Mygland, Tveita, Strand, Solberg, Olsen, Aizenshtadt, Fauskanger, Lund, Brinch, Lycke, Dybing, Nygaard, Bøe, Heintz, Hovig, Hammarström, Corthay, Krauss: "Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models." in: Communications biology, Vol. 3, Issue 1, pp. 196, (2020) (PubMed).

Details zu CD69

Target: CD69

Andere Bezeichnung: CD69 (CD69 Produkte)

Synonyme: 5830438K24Rik antikoerper, AI452015 antikoerper, AIM antikoerper, VEA antikoerper, BL-AC/P26 antikoerper, CLEC2C antikoerper, EA1 antikoerper, GP32/28 antikoerper, MLR-3 antikoerper, Cd69 molecule antikoerper, CD69 antigen antikoerper, CD69 molecule antikoerper, Cd69 antikoerper, CD69 antikoerper

Hintergrund: CD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. CD69 is widely expressed on hematopoietic cells, including lymphocytes, neutrophils and eosinophils. Although not detectable on resting lymphocytes, its expression is rapidly (within 2 hours) upregulated upon activation of T, B and NK cells, and neutrophils.4 Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells.