CD72.1 Antikörper

Produktnummer ABIN135264

Produktdetails anti-CD72.1 Antikörper

Target: CD72.1

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD72.1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Spezifität: Mouse CD72.1, Mr 45 kDa

Produktmerkmale: Mouse Anti-Mouse CD72.1-UNLB

Aufreinigung: Purified

Immunogen: DBA/2 mouse spleen cells

Klon: 10-1-D2

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IP - Reported in literature , Activ - Reported in literature , Block - Reported in literature , Costim - Reported in literature
• Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells APC and AF647 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

In vitro blocking and proliferation assays

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Konservierungsmittel: Without preservative

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Details zu CD72.1

Target: CD72.1

Abstract: CD72.1 Produkte

Hintergrund: CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. The 10-1.D.2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing.