CTLA4 Antikörper
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- Target Alle CTLA4 Antikörper anzeigen
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
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Reaktivität
- Maus
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Wirt
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Hamster
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Klonalität
- Monoklonal
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Konjugat
- Dieser CTLA4 Antikörper ist unkonjugiert
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Applikation
- ELISA
- Spezifität
- Mouse CD152, Mr 33-37 kDa
- Produktmerkmale
- Hamster Anti-Mouse CD152-UNLB
- Aufreinigung
- Purified
- Immunogen
- Heat-killed Staphylococcus A bacteria coated with mouse CTLA-4/human IgG1 fusion protein
- Klon
- 9H10
- Isotyp
- IgG
- Top Product
- Discover our top product CTLA4 Primärantikörper
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anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibody (PE)
CTLA4 Reaktivität: Human FACS Wirt: Maus Monoclonal BNI3 PE
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-135) antibodyCTLA4 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2F1 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibodyCTLA4 Reaktivität: Human FACS, IP, ICC, IHC (fro) Wirt: Maus Monoclonal BNI3 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) antibodyCTLA4 Reaktivität: Human FACS, IP, ICC, IHC (fro) Wirt: Maus Monoclonal BNI3 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 37-162) antibodyCTLA4 Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 9D2E9 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) antibodyCTLA4 Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 8B3F8 unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 36-161) antibodyCTLA4 Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM50 unconjugated Recombinant Antibody
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 41-90) antibodyCTLA4 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 52-211) antibodyCTLA4 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) (AA 75-170) antibodyCTLA4 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (p), IF (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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- Applications: ELISA - Quality tested , FC - Reported in literature , IP - Reported in literature , Costim - Reported in literature , Block - Reported in literature
- Working Dilutions: ELISA Purified (UNLB) antibody 1 g/mL
- Kommentare
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In vitro and in vivo blocking of CTLA-4 action by soluble antibody, Promotion of in vitro CTLA-4 signaling by cross-linked antibody
- Probenmenge
- 1 mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
- Konservierungsmittel
- Without preservative
- Handhabung
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C
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- Target
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
- Andere Bezeichnung
- CD152 (CTLA4 Produkte)
- Hintergrund
- CD152, also known as CTLA-4, is homologous to the costimulatory molecule CD28. Like CD28, the CD152 molecule binds the family of B7 counter-receptors (CD80/B7-1 and CD86/B7-2) on antigen-presenting cells. CTLA-4 is not expressed on resting T lymphocytes but is induced 2-3 days following T-cell stimulation via the T cell receptor (TCR) complex. Whereas CD28 provides a positive costimulatory signal, CD152/CTLA-4 is a negative regulator of T-cell activation, possibly by inhibiting tyrosine kinase signalling through the TCR through its association with tyrosine phosphatases such as SHP-2.
- Pathways
- Cancer Immune Checkpoints
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