NK-1.1/CD161c Antikörper

Produktnummer ABIN135344

Produktdetails anti-NK-1.1/CD161c Antikörper

Target: NK-1.1/CD161c (NK-1.1)

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NK-1.1/CD161c Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Spezifität: Mouse NK1.1, Mr 39 kDa

Produktmerkmale: Mouse Anti-Mouse NK1.1-LE/AF

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Endotoxin-Niveau: Low endotoxin

Immunogen: CE mouse spleen enriched for NK-1+ cells and bone marrow cells

Klon: PK136

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC - Reported in literature , IP - Reported in literature , Depletion - Reported in literature , CMCD - Reported in literature , Block - Reported in literature , Activ - Reported in literature
• Working Dilutions: Flow Cytometry FITC, BIOT, PACBLU, AF488, and AF700 conjugates 1 g/106 cells PE and APC conjugates 0.5 g/106 cells PE/CY7 and AF647 conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

Induction of proliferation of a subset of NK cells, In vivo depletion of NK1.1 cells, In vitro redirected lysis, In vitro cytotoxicity assays

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of PBS

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.

Details zu NK-1.1/CD161c

Target: NK-1.1/CD161c (NK-1.1)

Andere Bezeichnung: NK1.1 (NK-1.1/CD161c Produkte)

Synonyme: AI462337 antikoerper, CD161 antikoerper, Ly-59 antikoerper, Ly55c antikoerper, Ly59 antikoerper, NK-RP1 antikoerper, NK1.1 antikoerper, NKR-P1.9 antikoerper, NKRP1 antikoerper, NKRP140 antikoerper, Nk-1 antikoerper, Nk-1.2 antikoerper, Nk1 antikoerper, Nk1.2 antikoerper, Nkrp1c antikoerper, ly-55c antikoerper, killer cell lectin-like receptor subfamily B member 1C antikoerper, Klrb1c antikoerper

Hintergrund: NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL, NZB). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice.