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IL2 Receptor beta Antikörper

IL2RB Reaktivität: Maus FACS Wirt: Ratte Monoclonal 5H4 unconjugated
Produktnummer ABIN135408
  • Target Alle IL2 Receptor beta (IL2RB) Antikörper anzeigen
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    Reaktivität
    • 94
    • 85
    • 16
    • 5
    • 1
    Maus
    Wirt
    • 78
    • 37
    • 26
    Ratte
    Klonalität
    • 79
    • 61
    • 1
    Monoklonal
    Konjugat
    • 61
    • 14
    • 11
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL2 Receptor beta Antikörper ist unkonjugiert
    Applikation
    • 71
    • 71
    • 32
    • 26
    • 26
    • 19
    • 16
    • 10
    • 9
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Mouse CD122, 90-100 kDa
    Kreuzreaktivität (Details)
    Cross-reactivity with Stat1 from other sources has not been determined.
    Homologie
    A BLAST analysis was used to suggest cross-reactivity with Stat1 from mouse and rat based on 100% homology with the immunizing sequence. Partial reactivity is expected against Stat1 from human sources as 90% homology is noted.
    Produktmerkmale
    Rat Anti-Mouse CD122-UNLB
    Aufreinigung
    Purified
    Immunogen
    Rat myeloma YB2/0 transfected with truncated IL-2Rbeta cDNA (YB2/0-mbetat-28)
    Klon
    5H4
    Isotyp
    IgG2a
    Top Product
    Discover our top product IL2RB Primärantikörper
  • Applikationshinweise
    • Applications: FC - Quality tested , IP - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE and APC conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Probenmenge
    1 mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Konservierungsmittel
    Without preservative
    Handhabung
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C
  • Target
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    Andere Bezeichnung
    CD122 (IL2RB Produkte)
    Synonyme
    IL2RB antikoerper, il-2rb antikoerper, CD122 antikoerper, IL15RB antikoerper, P70-75 antikoerper, IL2RBC antikoerper, IL-15Rbeta antikoerper, IL15Rbeta antikoerper, Il-2/15Rbeta antikoerper, Il-2Rbeta antikoerper, p70 antikoerper, interleukin 2 receptor subunit beta antikoerper, interleukin-2 receptor subunit beta antikoerper, interleukin 2 receptor, beta antikoerper, interleukin 2 receptor, beta chain antikoerper, IL2RB antikoerper, LOC510185 antikoerper, il2rb antikoerper, Il2rb antikoerper
    Hintergrund
    The IL-2 receptor is a complex of three distinct polypeptide chains: (i) the chain which binds IL-2 with low affinity, (ii) the chain that binds IL-2 with high affinity, and (ii) the common chain (C) that does not bind IL-2. The high affinity receptor complex is an α/β/γ heterotrimer with a kDa of 1.3 x 10-11 M.2 In mouse spleen, CD122 is expresed on 30 % of CD8+ cells and all NK cells, but < 1 % of B cells and CD4+ T lymphocytes. In the thymus, its expression is confined to CD4-CD8+ single positive and CD4-CD8- double negative cells. Cytoplasmic regions of the IL-2R chain are involved in IL-2-mediated cellular signaling and, via the interaction of IL-2 and its receptor complex, may be involved in the generation and differentiation of T lymphocytes.
    Pathways
    JAK-STAT Signalweg, Growth Factor Binding
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