LAMP1 Antikörper

Produktnummer ABIN135442

Produktdetails anti-LAMP1 Antikörper

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser LAMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Spezifität: Mouse CD107a, Mr 110-140 kDa

Produktmerkmale: Rat Anti-Mouse CD107a-UNLB

Aufreinigung: Purified

Immunogen: Plasma membrane fraction of mouse embryo NIH/3T3 cell line

Klon: 1D4B

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Working Dilution:
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Kommentare:

Immunoelectron microscopy, Immunoaffinity chromatography

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Product is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Referenzen für anti-LAMP1 Antikörper (ABIN135442)

Song, Lee, Schindler: "Deletion of the murine scavenger receptor CD68." in: Journal of lipid research, Vol. 52, Issue 8, pp. 1542-50, (2011) (PubMed).

Details zu LAMP1

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Andere Bezeichnung: CD107a (LAMP1 Produkte)

Synonyme: CD107a antikoerper, LAMPA antikoerper, LGP120 antikoerper, AI196048 antikoerper, Lamp-1 antikoerper, LEP100 antikoerper, LAMP-1 antikoerper, LGP-A antikoerper, Lgpa antikoerper, Lysosome-associated membrane protein 1 antikoerper, cd107a antikoerper, lamp-1 antikoerper, lamp1 antikoerper, lampa antikoerper, lgp120 antikoerper, rexp76 antikoerper, lysosomal associated membrane protein 1 antikoerper, lysosomal-associated membrane protein 1 antikoerper, lysosomal-associated membrane protein 1 L homeolog antikoerper, LAMP1 antikoerper, Lamp1 antikoerper, lamp1.L antikoerper

Hintergrund: CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.

Pathways: Autophagie