Ezrin Antikörper (pTyr353)
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- Target Alle Ezrin (EZR) Antikörper anzeigen
- Ezrin (EZR)
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Bindungsspezifität
- pTyr353
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Ezrin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- The antibody detects endogenous level of Ezrin only when phosphorylated at tyrosine 353.
- Immunogen
- Peptide sequence around phosphorylation site of pTyr353 (Q-D-Y (p) -E-E) derived from Human EZRIN. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Top Product
- Discover our top product EZR Primärantikörper
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- Applikationshinweise
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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Differential ezrin and phosphorylated ezrin expression profiles between pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasm, and invasive ductal carcinoma of the pancreas." in: Human pathology, Vol. 44, Issue 8, pp. 1487-98, (2013) (PubMed).
: "Liver-intestine cadherin expression is associated with intestinal differentiation and carcinogenesis in intraductal papillary mucinous neoplasm." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 79, Issue 2, pp. 107-14, (2012) (PubMed).
: "Expression of Ezrin and phosphorylated Ezrin (pEzrin) in pancreatic ductal adenocarcinoma." in: Cancer investigation, Vol. 28, Issue 3, pp. 242-7, (2010) (PubMed).
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Differential ezrin and phosphorylated ezrin expression profiles between pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasm, and invasive ductal carcinoma of the pancreas." in: Human pathology, Vol. 44, Issue 8, pp. 1487-98, (2013) (PubMed).
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- Target
- Ezrin (EZR)
- Andere Bezeichnung
- Ezrin (EZR Produkte)
- Synonyme
- CVIL antikoerper, CVL antikoerper, VIL2 antikoerper, ezr antikoerper, vil2 antikoerper, wu:fc05c03 antikoerper, wu:fj31d06 antikoerper, cvil antikoerper, cvl antikoerper, Vil2 antikoerper, AW146364 antikoerper, R75297 antikoerper, p81 antikoerper, ezr.S antikoerper, ezrin antikoerper, ezrin b antikoerper, ezrin L homeolog antikoerper, EZR antikoerper, ezrb antikoerper, ezr antikoerper, Ezr antikoerper, ezr.L antikoerper
- Hintergrund
- Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
- Molekulargewicht
- 81 kDa
- NCBI Accession
- NP_001104
- UniProt
- P15311
- Pathways
- Maintenance of Protein Location
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