ChT Antikörper

Produktnummer ABIN135606

Produktdetails anti-ChT Antikörper

Target: ChT (High Affinity Choline Transporter (ChT))

Reaktivität: Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ChT Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Spezifität: Chicken/Quail ChT1, Mr 63 & 103 kDa

Produktmerkmale: Mouse Anti-Chicken ChT1-UNLB

Aufreinigung: Purified

Immunogen: Chicken thymocytes

Klon: CT1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IP - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Kommentare:

In vitro inhibition of T cell differentiation

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Konservierungsmittel: Without preservative

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Details zu ChT

Target: ChT (High Affinity Choline Transporter (ChT))

Andere Bezeichnung: ChT1 (ChT Produkte)

Synonyme: CHT antikoerper, CHT1 antikoerper, HMN7A antikoerper, hCHT antikoerper, Cht1 antikoerper, solute carrier family 5 member 7 antikoerper, solute carrier family 5 (choline transporter), member 7 antikoerper, SLC5A7 antikoerper, Slc5a7 antikoerper

Hintergrund: ChT1, a member of the Ig superfamily with one V-like and one C2-like domain, is a T cell antigen that is expressed on the surface of embryonic thymocytes (day 10). In young chickens, about 90 % of the thymocytes as well as a subpopulation of peripheral lymphocytes (which represent recent thymic emigrants) are ChT1 positive. Expression in the periphery declines with age and, in correlation with partial thymectomy, indicates that ChT1 can be used as an accurate marker for studying thymic function. CT1 can block T cell differentiation in vitro, in thymic organ cultures and in thymocyte precursors cultured on stromal cell monolayers. CT1 also recognizes quail cortical thymocytes.