CD74 Antikörper (Biotin)
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- Target Alle CD74 Antikörper anzeigen
- CD74 (HLA-DR-gamma (CD74))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD74 Antikörper ist konjugiert mit Biotin
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- Human CD74, Mr 41, 35, 33 kDa
- Produktmerkmale
- Mouse Anti-Human CD74-BIOT
- Aufreinigung
- Ion exchange column
- Immunogen
- Cell line SU-DHL-4 nuclei
- Klon
- LN2
- Isotyp
- IgG1
- Top Product
- Discover our top product CD74 Primärantikörper
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- Applikationshinweise
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, and PE conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 100 tests in 1.0 mL of PBS/Sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
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Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C
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- Target
- CD74 (HLA-DR-gamma (CD74))
- Andere Bezeichnung
- CD74 (CD74 Produkte)
- Hintergrund
- CD74 represents a type II integral membrane protein known as MHC Class II-associated invariant chain (Mr 43, 41, 35, 33 kDa). It is moderately expressed on B cells, and weakly on monocytes and macrophages. CD74 is also found on a subset of activated T cells, Langerhans cells, dendritic cells and some epithelial cells. CD74 may play a role in antigen processing and presentation through intracellular transport and expression of Class II molecules on the cell surface.
- Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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