UBXN6 Antikörper
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- Target Alle UBXN6 Antikörper anzeigen
- UBXN6 (UBX Domain Protein 6 (UBXN6))
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Reaktivität
- Human, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser UBXN6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- Spezifität
- Detects only full length isoform
- Kreuzreaktivität
- Maus
- Aufreinigung
- purified
- Immunogen
- recombinant protein purified from bacteria
- Klon
- 2F8-24
- Isotyp
- IgG1
- Top Product
- Discover our top product UBXN6 Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 0.5 % PBS, 50 % glycerol, 0.1 % BSA
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- short term: 2 °C - 8 °C, long term: -20 °C
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- Target
- UBXN6 (UBX Domain Protein 6 (UBXN6))
- Andere Bezeichnung
- UBXD1 (Full Length Isoform) (UBXN6 Produkte)
- Synonyme
- Ubxd1 antikoerper, UBXD1 antikoerper, UBXDC2 antikoerper, 1200008L11Rik antikoerper, 2210415J11Rik antikoerper, AU040909 antikoerper, Ubxdc2 antikoerper, UBX domain protein 6 antikoerper, Ubxn6 antikoerper, UBXN6 antikoerper
- Hintergrund
- P97 is a highly abundant and conserved member of the AAA family of ATPase. It has been termed an ubiquitin selective chaperone as it functions within the ubiquitin and/or proteasome pathway. p97 does not interact with ubiquitinated substrates on its own, but requires specific adapters that interact with ubiquitinated substrates and p97 and recruits p97 to substrates. One family of adapters contains a UBX domain, which has been shown with certain adapters to function as a p97-binding module. UBXD1 is a UBX domain containing protein and p97 adapter. This adapter is unique in that it does not harbor an ubiquitin association domain and binds p97 via its PUG domain (another p97 binding motif). Two isoforms of UBXD1 are produced in cells, a full-length form of approximately 54 kDa, and an alternatively spliced variant that lacks the amino-terminal translational start site, and encodes a 47 kDa protein that is derived from an internal translational initiation site. UBXD1 expression at the RNA level has been shown to trend lower in poor prognostic cancers, including those of the breast and prostate.
- UniProt
- Q9BZV1
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