CD130/gp130 Antikörper

Produktnummer ABIN1383684

Produktdetails anti-CD130/gp130 Antikörper

Target: CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD130/gp130 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP)

Spezifität: Recognises the Gp130, common subunit for IL-6, IL-11, OSM, LIF, CNTF, CT-1 receptors, a 130-140 kDa protein

Aufreinigung: Ion exchange chromatography

Sterilität: 0.22 μm filtered

Immunogen: Natural soluble gp130,Myeloma X63/AG.8653 x Balb/c spleen cells

Klon: B-K11

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Konservierungsmittel: Without preservative

Lagerung: 4 °C

Informationen zur Lagerung: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

Referenzen für anti-CD130/gp130 Antikörper (ABIN1383684)

Müller-Newen, Küster, Wijdenes, Schaper, Heinrich: "Studies on the interleukin-6-type cytokine signal transducer gp130 reveal a novel mechanism of receptor activation by monoclonal antibodies." in: The Journal of biological chemistry, Vol. 275, Issue 7, pp. 4579-86, (2000) (PubMed).

Guillet, Auguste, Mayo, Kreher, Gascan: "Ciliary neurotrophic factor is a regulator of muscular strength in aging." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 4, pp. 1257-62, (1999) (PubMed).

Chevalier, Fourcin, Robledo, Wijdenes, Pouplard-Barthelaix, Gascan: "Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein." in: The Journal of biological chemistry, Vol. 271, Issue 25, pp. 14764-72, (1996) (PubMed).

Müller-Newen, Köhne, Keul, Hemmann, Müller-Esterl, Wijdenes, Brakenhoff, Hart, Heinrich: "Purification and characterization of the soluble interleukin-6 receptor from human plasma and identification of an isoform generated through alternative splicing." in: European journal of biochemistry / FEBS, Vol. 236, Issue 3, pp. 837-42, (1996) (PubMed).

Details zu CD130/gp130

Target: CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))

Andere Bezeichnung: CD130 (IL6ST Produkte)

Synonyme: CD130 antikoerper, CDW130 antikoerper, GP130 antikoerper, IL-6RB antikoerper, 5133400A03Rik antikoerper, AA389424 antikoerper, BB405851 antikoerper, D13Ertd699e antikoerper, gp130 antikoerper, Ac1055 antikoerper, Gp130 antikoerper, Il-6rb antikoerper, IL-6 antikoerper, interleukin 6 signal transducer antikoerper, IL6ST antikoerper, Il6st antikoerper, il6st antikoerper

Hintergrund: Gp130

Molekulargewicht: 130-140 kDa

Pathways: JAK-STAT Signalweg, Cellular Glucan Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Cancer Immune Checkpoints