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LRRC59 Antikörper (AA 21-120)

LRRC59 Reaktivität: Maus, Ratte WB, IHC (p), ELISA, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1385303
  • Target Alle LRRC59 Antikörper anzeigen
    LRRC59 (Leucine Rich Repeat Containing 59 (LRRC59))
    Bindungsspezifität
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reaktivität
    • 13
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 13
    Kaninchen
    Klonalität
    • 13
    Polyklonal
    Konjugat
    • 13
    Dieser LRRC59 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human LRRC59
    Isotyp
    IgG
    Top Product
    Discover our top product LRRC59 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    LRRC59 (Leucine Rich Repeat Containing 59 (LRRC59))
    Andere Bezeichnung
    LRRC59 (LRRC59 Produkte)
    Synonyme
    p34 antikoerper, PRO1855 antikoerper, AA959742 antikoerper, C78668 antikoerper, leucine rich repeat containing 59 antikoerper, leucine rich repeat containing 59 S homeolog antikoerper, LRRC59 antikoerper, Lrrc59 antikoerper, lrrc59.S antikoerper
    Hintergrund

    Synonyms: Leucine-rich repeat-containing protein 59, LRC59_HUMAN, LRRC59, PRO1855.

    Background: LRRC59 (leucine rich repeat containing 59), also known as PRO1855, is a 307 amino acid protein that contains leucine-rich repeats and may play a role in protein binding events throughout the cell. The gene encoding LRRC59 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

    Gen-ID
    55379
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