UBR2 Antikörper
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- Target Alle UBR2 Antikörper anzeigen
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser UBR2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human UBR2
- Isotyp
- IgG
- Top Product
- Discover our top product UBR2 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
- Andere Bezeichnung
- UBR2 (UBR2 Produkte)
- Synonyme
- ba49a4.1 antikoerper, si:ch211-239i4.2 antikoerper, C6orf133 antikoerper, RP3-392M17.3 antikoerper, bA49A4.1 antikoerper, dJ242G1.1 antikoerper, dJ392M17.3 antikoerper, 9930021A08Rik antikoerper, AI462103 antikoerper, AW540746 antikoerper, E130209G04Rik antikoerper, mKIAA0349 antikoerper, ubiquitin protein ligase E3 component n-recognin 2 antikoerper, ubiquitin protein ligase E3 component n-recognin 2 S homeolog antikoerper, UBR2 antikoerper, ubr2 antikoerper, ubr2.S antikoerper, Ubr2 antikoerper
- Hintergrund
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Synonyms: E3 ubiquitin protein ligase UBR2, N recognin 2, Ubiquitin ligase E3 alpha II, Ubiquitin protein ligase E3 alpha 2, Ubiquitin protein ligase E3 component n recognin 2, UBR 2, UBR2_HUMAN, N-recognin-2, Ubiquitin-protein ligase E3-alpha-2, Ubiquitin-protein ligase E3-alpha-II.
Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.
- Gen-ID
- 23304
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