PGBD3 Antikörper (AA 410-460)

Produktnummer ABIN1385394

Produktdetails anti-PGBD3 Antikörper

Target: PGBD3 (PiggyBac Transposable Element Derived 3 (PGBD3))

Bindungsspezifität: AA 410-460

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PGBD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PGBD3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PGBD3

Target: PGBD3 (PiggyBac Transposable Element Derived 3 (PGBD3))

Andere Bezeichnung: PGBD3 (PGBD3 Produkte)

Synonyme: PGBD3 antikoerper, piggyBac transposable element derived 3 antikoerper, ERCC excision repair 6, chromatin remodeling factor antikoerper, PGBD3 antikoerper, ERCC6 antikoerper

Hintergrund:

Synonyms: PGBD 3, PiggyBac transposable element derived 3, PiggyBac transposable element derived protein 3, PGBD3_HUMAN.

Background: PiggyBac transposable element derived 3, also known as PGBD3, encodes a 593 amino acid transposase and is a member of the piggyBac transposable element derived (PGBD) gene family, which includes several genes that are derived from piggyBac transposons. Initially characterized in the cabbacge looper moth, Trichoplusia ni, the PGBD family is conserved in a wide variety of species, including protozoa and primates. More specifically, while PGBD3 and PGBD4 are primate-specific genes, the other three members of the PGBD family (namely PGBD1, PGBD2 and PGBD5) are conserved among a variety of vertebrates. PGBD3 appears to be novel, with no clear relationship to other transposases or other known protein families. However, the PGBD3 gene overlaps with the CSB gene on chromosome 10 and, with the CSB gene, plays a role in Cockayne syndrome, a rare disorder characterized by premature aging, microcephaly, photosensitivity and severe neurologic degeneration.

Gen-ID: 267004

UniProt: Q8N328

Pathways: Chromatin Binding