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C18orf1 Antikörper (AA 1-50)

C18orf1 Reaktivität: Human, Maus, Ratte WB, IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1385453
  • Target Alle C18orf1 Antikörper anzeigen
    C18orf1 (Chromosome 18 Open Reading Frame 1 (C18orf1))
    Bindungsspezifität
    • 14
    • 2
    • 1
    • 1
    AA 1-50
    Reaktivität
    • 22
    • 20
    • 20
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 20
    • 2
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser C18orf1 Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C18orf1
    Isotyp
    IgG
    Top Product
    Discover our top product C18orf1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    C18orf1 (Chromosome 18 Open Reading Frame 1 (C18orf1))
    Andere Bezeichnung
    C18orf1 (C18orf1 Produkte)
    Synonyme
    C18orf1 antikoerper, 8230401C20Rik antikoerper, A430083H02 antikoerper, A430108L08Rik antikoerper, D18Ertd653e antikoerper, D330030L18Rik antikoerper, low density lipoprotein receptor class A domain containing 4 antikoerper, LDLRAD4 antikoerper, Ldlrad4 antikoerper
    Hintergrund

    Synonyms: C18orf1, Low-density lipoprotein receptor class A domain-containing protein 4, LDLRAD4

    Background: Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.

    Gen-ID
    753
    UniProt
    O15165
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