C11orf57 Antikörper

Produktnummer ABIN1385534

Produktdetails anti-C11orf57 Antikörper

Target: C11orf57 (Chromosome 11 Open Reading Frame 57 (C11orf57))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C11orf57 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C11orf57

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu C11orf57

Target: C11orf57 (Chromosome 11 Open Reading Frame 57 (C11orf57))

Andere Bezeichnung: C11orf57 (C11orf57 Produkte)

Synonyme: NKAP domain containing 1 antikoerper, chromosome 24 C11orf57 homolog antikoerper, NKAP domain containing 1 L homeolog antikoerper, NKAPD1 antikoerper, C24H11orf57 antikoerper, nkapd1 antikoerper, nkapd1.L antikoerper

Hintergrund:

Synonyms: chromosome 11 open reading frame 57, CK057_HUMAN, FLJ10726, hypothetical protein LOC55216, Uncharacterized protein C11orf57.

Background: C11orf57, also known as FLJ10726, is a 292 amino acid protein that exists as three alternatively spliced isoforms and is encoded by a gene located on human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and _ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Gen-ID: 55216