LRRC3B Antikörper

Produktnummer ABIN1385812

Produktdetails anti-LRRC3B Antikörper

Target: LRRC3B (Leucine Rich Repeat Containing 3B (LRRC3B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRP15

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu LRRC3B

Target: LRRC3B (Leucine Rich Repeat Containing 3B (LRRC3B))

Andere Bezeichnung: LRP15 (LRRC3B Produkte)

Synonyme: LRP15 antikoerper, BC019794 antikoerper, RGD1311897 antikoerper, LRRC3B antikoerper, zgc:162270 antikoerper, leucine rich repeat containing 3B antikoerper, LRRC3B antikoerper, Lrrc3b antikoerper, lrrc3b antikoerper

Hintergrund:

Synonyms: LRP 15, LRP-15, Leucine rich repeat containing 3B, Leucine-rich repeat protein LRP15, Leucine-rich repeat-containing protein 3B, LRC3B_HUMAN, LRRC3B, MGC102927.

Background: Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutation in the genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 3B (LRRC3B), also designated LRP15, is a 259 amino acid protein that contains 3 LRR repeats. The gene encoding LRRC3B is a tumor suppressor gene that is regulated by DNA methylation. Decreased expression of LRRC3B has been shown in colorectal cancer and gastric cancer, making LRRC3B a candidate marker for those cancers.

Gen-ID: 116135