Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) Antikörper

Produktnummer ABIN1385978

Produktdetails

Target: Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCID1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)

Andere Bezeichnung: PCID1 (EIF3M Produkte)

Synonyme: ga17 antikoerper, pcid1 antikoerper, hfl-b5 antikoerper, tango7 antikoerper, MGC69424 antikoerper, PCID1 antikoerper, DKFZp459D197 antikoerper, Ga17 antikoerper, Pcid1 antikoerper, Tango7 antikoerper, B5 antikoerper, TANGO7 antikoerper, hfl-B5 antikoerper, GA17 antikoerper, fa16c10 antikoerper, wu:fa16c10 antikoerper, wu:fc41f09 antikoerper, zgc:63996 antikoerper, HFL-B5 antikoerper, RGD1565840 antikoerper, eukaryotic translation initiation factor 3 subunit M antikoerper, eukaryotic translation initiation factor 3, subunit M antikoerper, eukaryotic translation initiation factor 3 subunit M S homeolog antikoerper, eif3m antikoerper, EIF3M antikoerper, Eif3m antikoerper, eif3m.S antikoerper

Substanzklasse: Viral Protein

Hintergrund:

Synonyms: B5 receptor, Dendritic cell protein, e3m, E3M_HUMAN, Eukaryotic translation initiation factor 3 subunit M, Fetal lung protein B5, FLJ29030, GA17, hfl B5, hFL-B5, PCI domain containing 1 herpesvirus entry mediator, PCI domain-containing protein 1, PCID1.

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).

Gen-ID: 10480

Pathways: Ribonucleoprotein Complex Subunit Organization