GPS1 Antikörper (AA 324-370)
-
- Target Alle GPS1 Antikörper anzeigen
- GPS1 (G Protein Pathway Suppressor 1 (GPS1))
-
Bindungsspezifität
- AA 324-370
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser GPS1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CSN1
- Isotyp
- IgG
- Top Product
- Discover our top product GPS1 Primärantikörper
-
anti-G Protein Pathway Suppressor 1 (GPS1) (C-Term) antibody
GPS1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (AA 258-527) antibodyGPS1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) antibodyGPS1 Reaktivität: Human, Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (C-Term) antibodyVerified GPS1 Reaktivität: Human WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (AA 222-491) antibodyGPS1 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (AA 1-527) antibodyGPS1 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) antibodyGPS1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (AA 141-170) antibodyGPS1 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB32094 unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (AA 390-491) antibodyGPS1 Reaktivität: Human ELISA Wirt: Maus Monoclonal 1E8 unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (N-Term) antibodyGPS1 Reaktivität: Human, Maus, Rind (Kuh), Huhn, Zebrafisch (Danio rerio), Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- GPS1 (G Protein Pathway Suppressor 1 (GPS1))
- Andere Bezeichnung
- CSN1 (GPS1 Produkte)
- Hintergrund
-
Synonyms: CSN1, COPS1, COP9 signalosome complex subunit 1, SGN1, Signalosome subunit 1, G protein pathway suppressor 1, GPS-1, JAB1-containing signalosome subunit 1, Protein MFH, GPS1
Background: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction.
- Gen-ID
- 2873
- UniProt
- Q13098
- Pathways
- Zellzyklus
-
