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CSDC2 Antikörper (AA 21-120)

CSDC2 Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386053
  • Target Alle CSDC2 Antikörper anzeigen
    CSDC2 (Cold Shock Domain Containing C2, RNA Binding (CSDC2))
    Bindungsspezifität
    • 14
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    Reaktivität
    • 35
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 33
    • 2
    Kaninchen
    Klonalität
    • 33
    • 2
    Polyklonal
    Konjugat
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CSDC2 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 18
    • 17
    • 12
    • 12
    • 4
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PIPPIN
    Isotyp
    IgG
    Top Product
    Discover our top product CSDC2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CSDC2 (Cold Shock Domain Containing C2, RNA Binding (CSDC2))
    Andere Bezeichnung
    CSDC2/PIPPIN (CSDC2 Produkte)
    Synonyme
    pippin antikoerper, csdc2 antikoerper, zgc:91826 antikoerper, PIPPIN antikoerper, dJ347H13.2 antikoerper, AI415250 antikoerper, AI481750 antikoerper, Pippin antikoerper, cold shock domain containing C2, RNA binding antikoerper, cold shock domain containing C2 antikoerper, cold shock domain containing C2, RNA binding a antikoerper, cold shock domain containing C2 L homeolog antikoerper, CSDC2 antikoerper, csdc2 antikoerper, csdc2a antikoerper, csdc2.L antikoerper, Csdc2 antikoerper
    Hintergrund

    Synonyms: Cold shock domain containing C2 RNA binding, Cold shock domain containing protein C2, Cold shock domain-containing protein C2, CSDC 2, Csdc2, CSDC2_HUMAN, dJ347H13.2, PIPPIN, RNA binding protein PIPPin, RNA-binding protein PIPPin.

    Background: PIPPIN is a Y-box protein (also called cold-shock (CSD) domain-containing protein) and belongs to a family of highly conserved RNA-binding transcriptional regulators. Predominantly expressed in brain cells and localizing to the nucleus and the cytoplasm, PIPPIN contains two RNA-binding motifs, namely PIP1 and PIP2, and one CSD domain. PIPPIN functions as a nucleic acid binding regulatory factor and is believed to participate in brain maturation. More specifically, PIPPIN binds to the 3?-UTR ends of the mRNAs encoding Histone H1 and Histone H3.3. This interaction requires all of the PIPPIN domains to work in concert as one functional protein. In addition, PIPPIN can be sumoylated in a thyroid hormone (T3)-dependent manner. This suggests that PIPPIN modification in response to extracellular stimuli may modulate the regulation of protein synthesis.

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