CPT1C Antikörper (AA 121-170)

Produktnummer ABIN1386084

Produktdetails anti-CPT1C Antikörper

Target: CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

Bindungsspezifität: AA 121-170

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPT1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cpt1c

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CPT1C

Target: CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

Andere Bezeichnung: Cpt1c (CPT1C Produkte)

Synonyme: 6530437J22Rik antikoerper, 9630004I06Rik antikoerper, CATL1 antikoerper, CPT1-B antikoerper, CPT1P antikoerper, CPTI-B antikoerper, CPTIC antikoerper, CPT IC antikoerper, carnitine palmitoyltransferase 1c antikoerper, carnitine palmitoyltransferase 1C antikoerper, Cpt1c antikoerper, CPT1C antikoerper

Hintergrund:

Synonyms: CPT1-C, Carnitine acyltransferase like protein 1, Carnitine acyltransferase like protein1, Carnitine O palmitoyltransferase I, brain isoform, Carnitine palmitoyltransferase 1, brain, Carnitine palmitoyltransferase 1C, Carnitine palmitoyltransferase I related C, Carnitine palmitoyltransferase1C, CAT L1, CATL 1, CATL1, CPT 1 like pseudogene, Cpt 1c, CPT 1P, CPT I C, Cpt1 c, CPT1 like pseudogene, CPT1P , CPTIC.CPT1C_HUMAN

Background: The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.

Gen-ID: 126129

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process