NFATC4 Antikörper (AA 480-530)
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- Target Alle NFATC4 Antikörper anzeigen
- NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))
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Bindungsspezifität
- AA 480-530
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NFATC4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NF-ATc4
- Isotyp
- IgG
- Top Product
- Discover our top product NFATC4 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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Chronic intermittent hypoxia induces cardiac hypertrophy by impairing autophagy through the adenosine 5'-monophosphate-activated protein kinase pathway." in: Archives of biochemistry and biophysics, Vol. 606, pp. 41-52, (2016) (PubMed).
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Chronic intermittent hypoxia induces cardiac hypertrophy by impairing autophagy through the adenosine 5'-monophosphate-activated protein kinase pathway." in: Archives of biochemistry and biophysics, Vol. 606, pp. 41-52, (2016) (PubMed).
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- Target
- NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))
- Andere Bezeichnung
- NF-ATc4 (NFATC4 Produkte)
- Synonyme
- si:dkeyp-66d1.4 antikoerper, NFATC4 antikoerper, 3110041H08Rik antikoerper, AW107667 antikoerper, AW546455 antikoerper, Nfat3 antikoerper, NF-ATc4 antikoerper, NFAT3 antikoerper, nuclear factor of activated T-cells 4 antikoerper, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 antikoerper, NFATC4 antikoerper, nfatc4 antikoerper, Nfatc4 antikoerper
- Hintergrund
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Synonyms: NFAT3, NF-AT3, NF-ATC4, Nuclear factor of activated T-cells, cytoplasmic 4, NFATc4, T-cell transcription factor NFAT3
Background: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors, this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.
- Gen-ID
- 4776
- UniProt
- Q14934
- Pathways
- RTK Signalweg, WNT Signalweg
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