Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

MED7 Antikörper (AA 101-200)

MED7 Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386223
  • Target Alle MED7 Antikörper anzeigen
    MED7 (Mediator Complex Subunit 7 (MED7))
    Bindungsspezifität
    • 14
    • 10
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    AA 101-200
    Reaktivität
    • 50
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Human
    Wirt
    • 44
    • 6
    Kaninchen
    Klonalität
    • 46
    • 4
    Polyklonal
    Konjugat
    • 22
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MED7 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 23
    • 14
    • 12
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Zebrafish
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CRSP9
    Isotyp
    IgG
    Top Product
    Discover our top product MED7 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MED7 (Mediator Complex Subunit 7 (MED7))
    Andere Bezeichnung
    CRSP9 (MED7 Produkte)
    Synonyme
    ARC34 antikoerper, CRSP33 antikoerper, CRSP9 antikoerper, 1110063B05Rik antikoerper, Crsp33 antikoerper, Crsp9 antikoerper, crsp9 antikoerper, wu:fd99d12 antikoerper, zgc:56241 antikoerper, crsp9-A antikoerper, med7-a antikoerper, mediator complex subunit 7 antikoerper, mediator complex subunit 7 L homeolog antikoerper, mediator complex subunit antikoerper, mediator complex subunit Med7 antikoerper, MED7 antikoerper, Med7 antikoerper, med7 antikoerper, med7.L antikoerper
    Hintergrund

    Synonyms: Cofactor required for Sp1 transcriptional activation subunit 9, CRSP complex subunit 9, CRSP33, hMED7, MED7, MED7_HUMAN, Mediator complex subunit 7, Mediator of RNA polymerase II transcription subunit 7, MGC12284, RNA polymerase transcriptional regulation mediator subunit 7 homolog, Transcriptional coactivator CRSP33, Activator recruited cofactor 34 kDa component, Activator-recruited cofactor 34 kDa component, ARC34.

    Background: In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).

    Gen-ID
    9443
    Pathways
    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Sie sind hier:
Kundenservice