Syncoilin Antikörper

Produktnummer ABIN1386269

Produktdetails anti-Syncoilin Antikörper

Target: Syncoilin (Sync)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Syncoilin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SYNC/Syncoilin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Syncoilin

Target: Syncoilin (Sync)

Andere Bezeichnung: SYNC (Sync Produkte)

Synonyme: 1110057H03Rik antikoerper, SNIP4 antikoerper, SYNC1 antikoerper, SYNCOILIN antikoerper, syncoilin antikoerper, syncoilin, intermediate filament protein antikoerper, Sync antikoerper, SYNC antikoerper

Hintergrund:

Synonyms: Intermediate filament protein syncoilin, SYNC, SYNC1, SYNCI_HUMAN, Syncoilin, Syncoilin intermediate filament 1, Syncoilin-1.

Background: Syncoilin (SYNC) is a 483 amino acid member of the intermediate filament family. Localized to the perinuclear region of cytoplasm, Syncoilin interacts with Alpha-Dystrobrevin and Desmin. Syncoilin links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle, and is therefore found at high levels in cardiac and skeletal muscle. Syncoilin is upregulated at the sarcolemma in individuals with various forms of neuromuscular disease. The gene that encodes Syncoilin maps to human chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.